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Gold nanoparticle conjugate micro-optimization service

Optimizing your antibody-gold conjugates can be time consuming and difficult and can require significant amounts of time, antibody and gold. Innova Biosciences' micro-optimization service is a fast and efficient way to optimize your antibody conjugates using very small quantities of antibody.

For those scientists who require that little bit of extra performance, be it greater sensitivity or lower background, our micro-optimization service may well be the answer.

Using your preferred antibody and our high quality gold nanoparticles our micro-optimization service is performed by our experienced conjugation scientists here at Innova Biosciences. They use a combination of proprietary and traditional conjugation techniques to generate a range of different conjugates for you to test in your chosen application.

We have a range of gold micro-optimization services available including site specific orientated labeling. Find out more about each service below:

  • InnovaCoat® GOLD nanoparticle micro-optimization service [more]

  • InnovaCoat® GOLD Maleimide gold nanoparticle micro-optimization service [more]

  • InnovaCoat® GOLD Hydrazide gold nanoparticle micro-optimization service [more]

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InnovaCoat® GOLD nanoparticle micro-optimization service

Our gold nanoparticle micro-optimization service will provide you with 8 different antibody-gold nanoparticle conjugates produced at your chosen scale to test in your application.

Provide us with your own preferred antibody and our highly experienced conjugation scientists will generate a range of conjugates using our ultra-high quality gold nanoparticles.

Your chosen formulation can then be optimized further or scaled-up to suit your R&D or manufacturing needs.

Benefits of this service:

  • 8 different conjugates provided at your chosen scale
  • Level of conjugation controlled by a variety of parameters unique to Innova 
  • Fast turnaround time
  • Reproducible
  • Full technical support
  • Applicable to other proteins
  • Use your own preferred antibody (antibody can be provided if required*)
  • Scale-up your chosen formulation post conjugation (more info)

What’s included?

  • 8 different antibody-gold conjugates provided at either 50, 500, or 5000ul at 20OD
  • Select from 10, 20, 40, 60 or 80nm gold nanoparticles
  • Lateral flow strip provided for proof of successful conjugation
  • Unbound antibody removal post conjugation

Optional extras*

  • Antibody can be provided if required
  • Antibody clean-up prior to conjugation available
  • Scale-up your chosen formulation post conjugation (more info)

*additional costs apply

 


InnovaCoat® GOLD Maleimide gold nanoparticle micro-optimization service

Our Maleimide micro-optimization service will provide you with 6 different antibody-gold conjugates generated from your own preferred Fab’ and our 20nm or 40nm InnovaCoat® GOLD Maleimide.

This service requires your antibody to be provided as a Fab’ fragment. If you have a whole antibody but would like to try site specific labeling, we can generate the Fab’ for an additional cost. Please enquire for more information.

Your chosen formulation can then be optimized further or scaled-up to suit your R&D or manufacturing needs

Benefits of this service:

  • 6 different conjugates provided at your chosen scale
  • Level of conjugation controlled by a variety of parameters unique to Innova 
  • Fast turnaround time
  • Provided with a lateral flow assay proof of successful conjugation
  • Reproducible
  • Full technical support
  • Use your own preferred Fab’ (can be provided if required*)
  • Scale-up your chosen formulation post conjugation (more info)

What’s included?

  • 6 different conjugates provided at either 40, 400, or 1000ul at 20OD
  • Select from 20 or 40nm gold nanoparticles
  • Lateral flow strip provided for proof of successful conjugation
  • Unbound antibody removal post conjugation
  • 50ul or 500ul 20OD 40nm InnovaCoat® GOLD conjugate (if requested)
  • Antibody/Fab’ reduction and clean-up before conjugation*

Optional extras*

  • Generation of Fab’ fragment from your antibody
  • Fab’ purification prior to conjugation
  • 40nm InnovaCoat® GOLD conjugate, free from unbound antibody for comparison
  • Scale-up your chosen formulation post conjugation (more info)

*additional costs apply

 


InnovaCoat® GOLD Hydrazide gold nanoparticle micro-optimization service

Our Hydrazide micro-optimization service will provide you with 6 different antibody-gold conjugates generated from your own preferred antibody and our 40nm InnovaCoat® GOLD Hydrazide.

We will provide you with conjugates free of unbound antibody as a liquid at 20OD. Each conjugate will be perfectly scalable for future studies.

Benefits of this service:

  • 6 different conjugates provided at your chosen scale
  • Level of conjugation controlled by a variety of parameters unique to Innova 
  • Fast turnaround time
  • Reproducible
  • Full technical support
  • Applicable to other proteins
  • Scale-up your chosen formulation post conjugation (more info)

What’s included?

  • 8 different antibody-gold conjugates provided at either 50, 500, or 5000ul at 20OD
  • 40nm gold nanoparticles
  • Lateral flow strip provided for proof of successful conjugation
  • Unbound antibody removal post conjugation

Optional extras*

  • Antibody can be provided if required
  • Antibody clean-up prior to conjugation
  • Scale-up your chosen formulation post conjugation (more info)

*additional costs apply, please enquire

request quote

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