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Discover our thiol conjugation guide

Maleimide Activated Labels & Thiol Kits

Conjugate thiolated antibodies and proteins

buy now - maleimide and thiol-min



Maleimide activated labels

Maleimide activated labels are designed to facilitate the conjugation of the desired label to either antibodies, proteins, peptides or ligands that contain a sulfhydryl (-SH) group. The reactive maleimide groups that have been added to the label allows conjugation reactions to be performed very efficiently at physiological pH for superior performance.

Supplied as freeze dried formulations, therefore shipping on dry ice isn't necessary.

Maleimide Activated Labels & Thiol Kits Features and Benefits

Features Benefits
Compatible protein thiolation kit available No specialist knowledge required
Covalent bond Highly stable conjugates
Maleimide activated labels can be used with a range of biomolecules, including oligonucleotides Flexible
Scalable Easy transfer from R&D to manufacturing
Stringently QC tested Consistent high quality, excellent batch-to-batch reproducibility
Traditional, well-known conjugation chemistry Trusted method

Maleimide activated labels available:

Maleimide activated labels
Maleimide - RPE
Maleimide - HRP
Maleimide – Alkaline Phosphatase
Maleimide - APC
Maleimide – Streptavidin
Maleimide – Ovalbumin
Maleimide – BSA
Maleimide - KLH

 See also our Maleimide gold conjugation kits

 

Thiol kits

If the biomolecule does not have a free thiol group, it will require activation to generate a free thiol group prior to conjugation with the maleimide label:

1. Protein Thiolation kit [view protocol]

Designed to facilitate the conjugation of proteins to our maleimide-activated labels.  Simply add your protein solution to the lyophilized thiolation reagents to activate your protein. These kits are designed to activate 2mg or 5mg of your protein. 

Each thiolation kit is also supplied with a thiolation detection kit provided as a positive test for protein thiolation, giving you the option to confirm the chemistry is working.

2. Thiol quantification kit [view protocol]

The thiol quantification assay kit allows you to quantify the amount of thiol/sulfhydryl (-SH) groups in samples of thiolated proteins or antibodies. Quantifying the number of free thiols in a sample can be useful in a number of applications and allows for a more controlled conjugation reaction.

The assay is in a convenient 96-well plate format and contains all the necessary reagents required. 

 Please do not hesitate to Contact us to find out more!

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Bulk Quantities

We use specialized techniques that enable the quick and easy production of large quantities of maleimide activated labels, without compromising on quality. To request pricing on large quantities please get in touch.

bulk volume - thiol kits-min

Maleimide activate labelsMSDSProtocol
Maleimide Activated Alkaline Phosphatase
Maleimide Activated Allophycocyanin XL
Maleimide Activated BSA
Maleimide Activated HRP
Maleimide Activated KLH
Maleimide Activated Ovalbumin
Maleimide Activated RPE
Maleimide Activated Streptavidin
Protein Thiolation Kit
Clean-Up Reagent
Protein Resuspension Buffer
Thiol Detection Buffer
Thiol Detection Reagent
Thiolation Reagent
Thiol Quantification Kit
10x DTNB Reaction Buffer
50x DTNB
Lyophilized Cysteine
Buy Online

Maleimide-HRP (2mg) (401-0002)

In stock

£132.00

Maleimide-HRP (5mg) (401-0005)

In stock

£254.00

Maleimide-Alkaline Phosphatase (2mg) (402-0002)

In stock

£242.00

Maleimide Alkaline Phosphatase (5mg) (402-0005)

In stock

£474.00

Maleimide-R Phycoerythrin (2mg) (403-0002)

In stock

£276.00

Maleimide-R Phycoerythrin (5mg) (403-0005)

In stock

£551.00

Maleimide-Allophycocyanin-XL (2mg) (404-0002)

In stock

£386.00

Maleimide-Streptavidin (2mg) (405-0002)

In stock

£276.00

Maleimide-Streptavidin (5mg) (405-0005)

In stock

£584.00

Maleimide-Ovalbumin (2mg) (407-0002)

In stock

£143.00

Maleimide-Ovalbumin (5mg) (407-0005)

In stock

£204.00

Maleimide-BSA (2mg) (408-0002)

In stock

£132.00

Maleimide-BSA (5mg) (408-0005)

In stock

£187.00

Maleimide-KLH (2mg) (409-0002)

In stock

£143.00

Maleimide-KLH (5mg) (409-0005)

In stock

£204.00

Thiol quantification kit (192 assays) (418-0002)

In stock

£179.00

Protein Thiolation kit (5mg) (419-0005)

In stock

£263.00

Protein Thiolation Kit (2mg) (419-0002)

In stock

£210.00
Our shipping times are as follows:
48 hours to the US. 24 to 48 hours to Europe.
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